Claudication

Claudication is one of the earliest and most common symptoms of PAD. Reduced blood flow makes it harder for the leg muscles to get the oxygen they need during activity. This often causes cramping, tightness, or fatigue in the calves or thighs when walking. Symptoms usually improve with rest but return once activity begins again.

Claudication is a sign that the arteries are narrowing. Early evaluation can help prevent symptoms from progressing.

Rest Pain

As PAD becomes more advanced, blood flow to the legs may be reduced even when the body is at rest. This can cause burning, aching, or throbbing pain that is usually worse when lying down at night. Many patients find relief by hanging their legs over the side of the bed, which increases circulation with the help of gravity.

Rest pain is an important warning sign of significantly reduced circulation. Evaluation and timely treatment improve the chances of protecting limb health and preventing further complications.

Ulceration

When blood flow becomes severely limited, wounds on the toes, feet, or legs may not heal properly. These ulcers can become painful and infected if not treated early. Poor healing is often one of the most serious signs of advanced PAD and requires prompt medical attention.

Early diagnosis and treatment can help prevent wounds from forming or worsening.

Evaluation and Treatment

At San Francisco Vein & Vascular Institute, we specialize in the diagnosis and treatment of PAD. Our experienced team uses advanced imaging and noninvasive vascular testing to understand blood flow and identify blockages.

Treatment options may include lifestyle guidance, medications that improve circulation, and modern minimally invasive procedures designed to open narrowed arteries. These techniques can reduce pain, improve walking ability, and help protect long-term limb health. When needed, surgical options are also available.

If you have leg pain when walking, nighttime foot discomfort, slow-healing wounds, or risk factors such as smoking or diabetes, an evaluation can provide clarity and peace of mind.

Who is at Risk for PAD

PAD is more likely to occur in people who have:

  • Age over 50

  • A history of smoking

  • Diabetes

  • High blood pressure

  • High cholesterol

  • Kidney disease

  • A family history of vascular disease

  • Leg pain when walking that improves with rest

  • Wounds on the feet or toes that heal slowly

Signs You Should Not Ignore

You should schedule a vascular evaluation if you notice:

  • Cramping or tightness in your calves or thighs when walking

  • Burning or aching pain in the feet at night

  • Coldness or color changes in one leg

  • Slow-healing wounds on the toes or feet

  • Reduced ability to walk the distances you used to

  • A history of smoking combined with leg discomfort

More than 20 million Americans are affected by peripheral arterial disease
Modern minimally invasive treatments can improve circulation and reduce symptoms
PAD is evaluated and treated by experienced vascular specialists at SFVVI